Direct assessment of tubuloglomerular feedback responsiveness in connexin 40-deficient mice
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Direct assessment of tubuloglomerular feedback responsiveness in connexin 40-deficient mice.
Participation of connexin 40 (Cx40) in the regulation of renin secretion and in the tubuloglomerular feedback (TGF) component of renal autoregulation suggests that gap junctional coupling through Cx40 contributes to the function of the juxtaglomerular apparatus. In the present experiments, we determined the effect of targeted Cx40 deletion in C57BL/6 and FVB mice on TGF responsiveness. In C57BL...
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14 Running title: Connexin 40 and tubuloglomerular feedback 15 16 Send all correspondence to: 17 Jurgen Schnermann, MD. 18 National Institute of Diabetes and Digestive and Kidney Diseases 19 National Institutes of Health 20 Building 10, Room 4D51 21 9000 Rockville Pike 22 Bethesda. MD 20892, USA 23 (Tel) 1-301-435-6580 24 (Fax) 1-301-435-6587 25 (E-mail)[email protected] 26 Abstract 2...
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ژورنال
عنوان ژورنال: American Journal of Physiology-Renal Physiology
سال: 2013
ISSN: 1931-857X,1522-1466
DOI: 10.1152/ajprenal.00721.2012